SNTA1 Antikörper

Produktnummer ABIN7270692

Produktdetails anti-SNTA1 Antikörper

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: Syntrophin alpha 1 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human Syntrophin alpha 1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SNTA1

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Andere Bezeichnung: Syntrophin alpha 1 (SNTA1 Produkte)

Synonyme: SNTA1 antikoerper, MGC147484 antikoerper, AW228934 antikoerper, Snt1 antikoerper, LQT12 antikoerper, SNT1 antikoerper, TACIP1 antikoerper, dJ1187J4.5 antikoerper, syntrophin alpha 1 antikoerper, syntrophin, alpha 1 L homeolog antikoerper, syntrophin, alpha 1 antikoerper, syntrophin, acidic 1 antikoerper, SNTA1 antikoerper, snta1.L antikoerper, snta1 antikoerper, Snta1 antikoerper

Hintergrund: Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013],LQT12, SNT1, TACIP1, dJ1187J4.5,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,Syntrophin alpha 1

Molekulargewicht: 54kDa

Gen-ID: 6640

UniProt: Q13424

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development