RMND5A Antikörper (AA 200-270)

Produktnummer ABIN7269917

Produktdetails anti-RMND5A Antikörper

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Bindungsspezifität: AA 200-270

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RMND5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: RMND5A Rabbit pAb

Sequenz: ISLLMGGTTN QREALQYAKN FQPFALNHQK DIQVLMGSLV YLRQGIENSP YVHLLDANQW ADICDIFTRD A

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-270 of human RMND5A (NP_073617.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RMND5A

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Andere Bezeichnung: RMND5A (RMND5A Produkte)

Synonyme: CTLH antikoerper, GID2 antikoerper, GID2A antikoerper, RMD5 antikoerper, p44CTLH antikoerper, 1110007A06Rik antikoerper, AJ237586 antikoerper, AW125795 antikoerper, Gid2 antikoerper, MTA.D02.090 antikoerper, required for meiotic nuclear division 5 homolog A antikoerper, RMND5A antikoerper, Rmnd5a antikoerper

Hintergrund: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.,RMND5A,CTLH,GID2,GID2A,RMD5,p44CTLH,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,RMND5A

Molekulargewicht: 10kDa/43kDa

Gen-ID: 64795

UniProt: Q9H871