RAPGEF3 Antikörper

Produktnummer ABIN7269850

Produktdetails anti-RAPGEF3 Antikörper

Target: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser RAPGEF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Epac1/RAPGEF3 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Epac1/RAPGEF3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RAPGEF3

Target: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Andere Bezeichnung: RAPGEF3 (RAPGEF3 Produkte)

Synonyme: RAPGEF3 antikoerper, epac antikoerper, si:dkey-27m20.2 antikoerper, CAMP-GEFI antikoerper, EPAC antikoerper, EPAC1 antikoerper, HSU79275 antikoerper, bcm910 antikoerper, 2310016P22Rik antikoerper, 9330170P05Rik antikoerper, Epac antikoerper, Epac1 antikoerper, Rap guanine nucleotide exchange factor 3 antikoerper, Rap guanine nucleotide exchange factor 3 S homeolog antikoerper, Rap guanine nucleotide exchange factor (GEF) 3 antikoerper, RAPGEF3 antikoerper, rapgef3.S antikoerper, rapgef3 antikoerper, Rapgef3 antikoerper

Hintergrund: Guanine nucleotide exchange factor (GEF for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.,CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910,Endocrine & Metabolism,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,MAPK-Erk Signaling Pathway,Signal Transduction,RAPGEF3

Molekulargewicht: 104kDa

Gen-ID: 10411

UniProt: O95398

Pathways: cAMP Metabolic Process