Phospholipase C gamma 2 Antikörper (pTyr759)

Produktnummer ABIN7269341

Produktdetails anti-Phospholipase C gamma 2 Antikörper

Target: Phospholipase C gamma 2 (PLCG2)

Bindungsspezifität: pTyr759

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Phospho-PLC gamma 2 (PLCG2)-Y759 Rabbit pAb

Sequenz: RMYVD

Kreuzreaktivität: Human

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic phosphorylated peptide around Y759 of human PLC gamma 2 (PLCG2) (NP_002652.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Phospholipase C gamma 2

Target: Phospholipase C gamma 2 (PLCG2)

Andere Bezeichnung: PLCG2 (PLCG2 Produkte)

Synonyme: PLCgamma2 antikoerper, Plcg-2 antikoerper, APLAID antikoerper, FCAS3 antikoerper, phospholipase C, gamma 2 antikoerper, phospholipase C gamma 2 antikoerper, phospholipase C, gamma 2 (phosphatidylinositol-specific) antikoerper, Plcg2 antikoerper, PLCG2 antikoerper

Hintergrund: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.,PLCG2,APLAID,FCAS3,PLC-IV,PLC-gamma-2,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Lipids,Protein phosphorylation,PLCG2

Molekulargewicht: 147kDa

Gen-ID: 5336

UniProt: P16885

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling