Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

NPC1 Antikörper

NPC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7268911
  • Target Alle NPC1 Antikörper anzeigen
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    Reaktivität
    • 47
    • 19
    • 14
    • 2
    Human
    Wirt
    • 41
    • 6
    • 2
    Kaninchen
    Klonalität
    • 35
    • 14
    Monoklonal
    Konjugat
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NPC1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 28
    • 20
    • 14
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Verwendungszweck
    Niemann Pick C1 Rabbit mAb
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Niemann Pick C1.
    Isotyp
    IgG
    Top Product
    Discover our top product NPC1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    Andere Bezeichnung
    Niemann Pick C1 (NPC1 Produkte)
    Synonyme
    NPC antikoerper, 9130221N23Rik antikoerper, Gm243 antikoerper, Cdig2 antikoerper, im:7149020 antikoerper, wu:fb53a12 antikoerper, wu:fc29a12 antikoerper, A430089E03Rik antikoerper, C85354 antikoerper, D18Ertd139e antikoerper, D18Ertd723e antikoerper, lcsd antikoerper, nmf164 antikoerper, spm antikoerper, NPC intracellular cholesterol transporter 1 antikoerper, NPC1 like intracellular cholesterol transporter 1 antikoerper, Niemann-Pick disease, type C1 antikoerper, Niemann-Pick C1 protein antikoerper, NPC1 antikoerper, Npc1l1 antikoerper, Npc1 antikoerper, npc1 antikoerper, LOC579887 antikoerper
    Hintergrund
    This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.,NPC1, NPC, Niemann-Pick C1 protein,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,Lipids,Fatty Acids,Cardiovascular diseases,Heart disease,Niemann Pick C1
    Molekulargewicht
    180kDa
    Gen-ID
    4864
    UniProt
    O15118