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GCH1 Antikörper (AA 1-250)

GCH1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7267525
  • Target Alle GCH1 Antikörper anzeigen
    GCH1 (GTP Cyclohydrolase 1 (GCH1))
    Bindungsspezifität
    • 15
    • 11
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 1-250
    Reaktivität
    • 39
    • 24
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 7
    • 1
    Kaninchen
    Klonalität
    • 52
    • 3
    Polyklonal
    Konjugat
    • 21
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GCH1 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 29
    • 18
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    Western Blotting (WB), Immunofluorescence (IF)
    Verwendungszweck
    GCH1 Rabbit pAb
    Sequenz
    MEKGPVRAPA EKPRGARCSN GFPERDPPRP GPSRPAEKPP RPEAKSAQPA DGWKGERPRS EEDNELNLPN LAAAYSSILS SLGENPQRQG LLKTPWRAAS AMQFFTKGYQ ETISDVLNDA IFDEDHDEMV IVKDIDMFSM CEHHLVPFVG KVHIGYLPNK QVLGLSKLAR IVEIYSRRLQ VQERLTKQIA VAITEALRPA GVGVVVEATH MCMVMRGVQK MNSKTVTSTM LGVFREDPKT REEFLTLIRS
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GCH1 (NP_000152.1).
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GCH1 (GTP Cyclohydrolase 1 (GCH1))
    Andere Bezeichnung
    GCH1 (GCH1 Produkte)
    Synonyme
    DYT14 antikoerper, DYT5 antikoerper, DYT5a antikoerper, GCH antikoerper, GTP-CH-1 antikoerper, GTPCH1 antikoerper, HPABH4B antikoerper, GTP-CH antikoerper, GTPCH antikoerper, Gch antikoerper, MGC89622 antikoerper, gch1a antikoerper, wu:fc16b10 antikoerper, zgc:195269 antikoerper, GTP cyclohydrolase 1 antikoerper, GTP cyclohydrolase 1-like antikoerper, GCH1 antikoerper, Gch1 antikoerper, gch1 antikoerper, Weevi_1190 antikoerper, Halhy_0838 antikoerper, Sinme_1220 antikoerper, Sphch_1077 antikoerper, LOC100136794 antikoerper
    Hintergrund
    This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.,GCH1,DYT14,DYT5,DYT5a,GCH,GTP-CH-1,GTPCH1,HPABH4B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,GCH1
    Molekulargewicht
    23kDa/25kDa/27kDa
    Gen-ID
    2643
    UniProt
    P30793
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