IFNA Antikörper (AA 101-189)

Produktnummer ABIN717131

Produktdetails anti-IFNA Antikörper

Target: IFNA (Interferon alpha (IFNA))

Bindungsspezifität: AA 101-189

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody will detect Human IFN-Alpha subtypes 2,4,5,6,7,8,10,14,16,17 and has lower affinity for IFNA1/13. This antibody will detect Mouse IFN-Alpha subtypes 1,2,5,7,12,13,14,16

Kreuzreaktivität: Maus

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFNA4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IFNA

Target: IFNA (Interferon alpha (IFNA))

Andere Bezeichnung: IFN-Alpha (IFNA Produkte)

Synonyme: IFN-alphaO antikoerper, IFN-ALPHA-1 antikoerper, IFN1@ antikoerper, Ifa antikoerper, Ifa8 antikoerper, interferon alpha 16 antikoerper, interferon, alpha 1 antikoerper, interferon alpha antikoerper, interferon-alpha antikoerper, IFNA16 antikoerper, IFNA1 antikoerper, Ifna antikoerper, IFNA antikoerper

Hintergrund:

Synonyms: IFNA, IFN-a, IFN-_, Interferon alpha, Interferon-alpha, IFNA2, IFNA4, IFNA6, IFNA7, IFNA8, IFNA10, IFNA16, IFNA17, IFNA5, IFNA21, IFNA14, IFNA1, IFNA13, Pan Interferon alpha

Background: Interferon-_ (IFN-_, also known as IFN-alpha, IFN-a, IFNA and Interferon-alpha) is a type I interferon and exists as 13 subtypes: IFN-_ 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17 and 21. They are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-_ to its receptor initiates an anti-viral response, but also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell.

Gen-ID: 3441

UniProt: P05014

Pathways: JAK-STAT Signalweg, TLR Signalweg, Hepatitis C, Inflammasome