ATP11C Antikörper (AA 430-650)

Produktnummer ABIN7265757

Produktdetails anti-ATP11C Antikörper

Target: ATP11C (ATPase, class VI, type 11C (ATP11C))

Bindungsspezifität: AA 430-650

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP11C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: ATP11C Rabbit pAb

Sequenz: DGHKYKGVTQ EVDGLSQTDG TLTYFDKVDK NREELFLRAL CLCHTVEIKT NDAVDGATES AELTYISSSP DEIALVKGAK RYGFTFLGNR NGYMRVENQR KEIEEYELLH TLNFDAVRRR MSVIVKTQEG DILLFCKGAD SAVFPRVQNH EIELTKVHVE RNAMDGYRTL CVAFKEIAPD DYERINRQLI EAKMALQDRE EKMEKVFDDI ETNMNLIGAT A

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 430-650 of human ATP11C (NP_775965.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ATP11C

Target: ATP11C (ATPase, class VI, type 11C (ATP11C))

Andere Bezeichnung: ATP11C (ATP11C Produkte)

Synonyme: A330005H02Rik antikoerper, AI315324 antikoerper, Ig antikoerper, Atp11c-ps1 antikoerper, RGD1564481 antikoerper, ATPase, class VI, type 11C antikoerper, ATPase phospholipid transporting 11C antikoerper, Atp11c antikoerper

Hintergrund: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS and phosphatidylethanolamines (PE, from the outer to the inner leaflet of the plasma membrane. Major PS-flippase in immune cell subsets. In erythrocyte plasma membrane, it is required to maintain PS in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for erythrocyte clearance by splenic macrophages. Required for B cell differentiation past the pro-B cell stage (By similarity. Seems to mediate PS flipping in pro-B cells (By similarity. May be involved in the transport of cholestatic bile acids (By similarity.,ATP11C,ATPIG,ATPIQ,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,ATP11C

Molekulargewicht: 126kDa/128kDa/129kDa

Gen-ID: 286410

UniProt: Q8NB49