GTPase NRas Antikörper

Produktnummer ABIN7191712

Produktdetails anti-GTPase NRas Antikörper

Target: GTPase NRas (NRAS)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTPase NRas Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human NRAS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GTPase NRas

Target: GTPase NRas (NRAS)

Andere Bezeichnung: NRAS (NRAS Produkte)

Synonyme: NRAS antikoerper, AV095280 antikoerper, N-ras antikoerper, ALPS4 antikoerper, NRAS1 antikoerper, NS6 antikoerper, N-RAS antikoerper, fj99a10 antikoerper, wu:fj99a10 antikoerper, zgc:100761 antikoerper, zras-b1 antikoerper, H-RAS antikoerper, HRAS antikoerper, GTPase NRas antikoerper, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog antikoerper, NRAS proto-oncogene, GTPase antikoerper, neuroblastoma ras oncogene antikoerper, neuroblastoma RAS viral oncogene homolog antikoerper, Tsp_01117 antikoerper, nras.L antikoerper, Nras antikoerper, NRAS antikoerper, nras antikoerper

Hintergrund:

Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Aliases: ALPS4 antibody, AV095280 antibody, GTPase NRas antibody, HRAS1 antibody, N ras antibody, N ras protein part 4 antibody, Neuroblastoma RAS viral (v ras) oncogene homolog antibody, NRAS antibody, NRAS1 antibody, NS6 antibody, OTTHUMP00000013879 antibody, OTTMUSP00000023521 antibody, RASN_HUMAN antibody, Transforming protein N Ras antibody, Transforming protein N-Ras antibody, v ras neuroblastoma RAS viral oncogene homolog antibody

UniProt: P01111

Pathways: p53 Signalweg, MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling