NOTCH4 Antikörper

Produktnummer ABIN7191676

Produktdetails anti-NOTCH4 Antikörper

Target: NOTCH4 (Notch 4 (NOTCH4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOTCH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human NOTCH4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NOTCH4

Target: NOTCH4 (Notch 4 (NOTCH4))

Andere Bezeichnung: NOTCH4 (NOTCH4 Produkte)

Synonyme: INT3 antikoerper, NOTCH3 antikoerper, Int-3 antikoerper, Int3 antikoerper, N4 antikoerper, Notch4 antikoerper, notch 4 antikoerper, neurogenic locus notch homolog protein 4 antikoerper, NOTCH4 antikoerper, Notch4 antikoerper, LOC100712850 antikoerper

Hintergrund:

Background: This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined.

Aliases: FLJ16302 antibody, hNotch 4 antibody, hNotch4 antibody, INT3 antibody, Neurogenic locus notch homolog protein 4 antibody, NOTC4_HUMAN antibody, Notch 4 antibody, Notch 4 intracellular domain antibody, Notch homolog 4 antibody, Notch4 antibody, NOTCH4 protein antibody

UniProt: Q99466

Pathways: Notch Signalweg