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MBNL3 Antikörper (AA 251-354)

MBNL3 Reaktivität: Maus ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN713756
  • Target Alle MBNL3 Antikörper anzeigen
    MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    AA 251-354
    Reaktivität
    • 30
    • 1
    Maus
    Wirt
    • 28
    • 2
    Kaninchen
    Klonalität
    • 29
    • 1
    Polyklonal
    Konjugat
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MBNL3 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MBNL3
    Isotyp
    IgG
    Top Product
    Discover our top product MBNL3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))
    Andere Bezeichnung
    MBNL3 (MBNL3 Produkte)
    Synonyme
    A530038J18Rik antikoerper, AI661274 antikoerper, CHCR antikoerper, E430034C16Rik antikoerper, MBLX antikoerper, MBLX39 antikoerper, MBXL antikoerper, mbxl antikoerper, RGD1565834 antikoerper, muscleblind like splicing regulator 3 antikoerper, muscleblind like splicing factor 3 antikoerper, Muscleblind-like protein 3-like antikoerper, muscleblind-like splicing regulator 3 antikoerper, MBNL3 antikoerper, Mbnl3 antikoerper, mbnl3 antikoerper
    Hintergrund

    Synonyms: MBLX, CHCR, Cys3His CCG1 required protein, MBLX39, MBNL 3, MBXL, Muscleblind like protein 3, Muscleblind like X linked protein, Protein HCHCR, MBNL3_HUMAN.

    Background: MBNL3 has been shown to inhibit muscle differentiation. MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators. This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, neurons, adipocytes and blood cell types. MBNL3 is expressed in myoblasts, muscle precursor cells, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes. MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies.

    Gen-ID
    55796
    UniProt
    Q9NUK0
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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