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VPS33A Antikörper (AA 1-300) (HRP)

VPS33A Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7175311
  • Target Alle VPS33A Antikörper anzeigen
    VPS33A (Vacuolar Protein Sorting 33 Homolog A (VPS33A))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 1
    AA 1-300
    Reaktivität
    • 17
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 15
    • 2
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VPS33A Antikörper ist konjugiert mit HRP
    Applikation
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Vacuolar protein sorting-associated protein 33A protein (1-300AA)
    Isotyp
    IgG
    Top Product
    Discover our top product VPS33A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    VPS33A (Vacuolar Protein Sorting 33 Homolog A (VPS33A))
    Andere Bezeichnung
    VPS33A (VPS33A Produkte)
    Synonyme
    r-Vps33a antikoerper, VPS33A antikoerper, vps33a antikoerper, MGC145524 antikoerper, 3830421M04Rik antikoerper, AI503300 antikoerper, AW048546 antikoerper, AW554476 antikoerper, bf antikoerper, im:7136893 antikoerper, wu:fc08g01 antikoerper, wu:fc26c10 antikoerper, VPS33A CORVET/HOPS core subunit antikoerper, VPS33A, CORVET/HOPS core subunit antikoerper, vacuolar protein sorting 33 homolog A (S. cerevisiae) antikoerper, Vacuolar protein sorting 33A antikoerper, VPS33A, CORVET/HOPS core subunit L homeolog antikoerper, vacuolar protein sorting 33A antikoerper, Vps33a antikoerper, VPS33A antikoerper, vps33a antikoerper, CGB_E2330C antikoerper, vps33a.L antikoerper
    Hintergrund

    Background: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes, the function is dependent on its association with VPS16 but not VIPAS39 (PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG (PubMed:24554770).

    Aliases: VPS33AVacuolar protein sorting-associated protein 33A antibody, hVPS33A antibody

    UniProt
    Q96AX1
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