SART3 Antikörper (AA 600-900) (Biotin)

Produktnummer ABIN7170664

Produktdetails anti-SART3 Antikörper (Biotin)

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Bindungsspezifität: AA 600-900

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SART3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Squamous cell carcinoma antigen recognized by T-cells 3 protein (600-900AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SART3

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Andere Bezeichnung: SART3 (SART3 Produkte)

Synonyme: SART3 antikoerper, DKFZp469J2418 antikoerper, si:ch211-191d15.4 antikoerper, wu:fc51h03 antikoerper, DSAP1 antikoerper, P100 antikoerper, RP11-13G14 antikoerper, TIP110 antikoerper, p110 antikoerper, p110(nrb) antikoerper, AU045857 antikoerper, mKIAA0156 antikoerper, squamous cell carcinoma antigen recognized by T-cells 3 antikoerper, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog antikoerper, squamous cell carcinoma antigen recognized by T cells 3 antikoerper, SART3 antikoerper, sart3 antikoerper, sart3.L antikoerper, Sart3 antikoerper

Hintergrund:

Background: U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).

Aliases: DSAP1 antibody, hSART 3 antibody, hSART-3 antibody, P100 antibody, P110 antibody, p110(nrb) antibody, RP11 13G14 antibody, SART 3 antibody, SART-3 antibody, SART3 antibody, SART3_HUMAN antibody, Squamous cell carcinoma antigen recognized by T cells 3 antibody, Squamous cell carcinoma antigen recognized by T-cells 3 antibody, Tat interacting protein of 110 kDa antibody, Tat-interacting protein of 110 kDa antibody, Tip110 antibody

UniProt: Q15020

Pathways: Ribonucleoprotein Complex Subunit Organization