PTHLH Antikörper (AA 37-175)

Produktnummer ABIN7347993

Produktdetails anti-PTHLH Antikörper

Target: PTHLH (Parathyroid Hormone-Like Hormone (PTHLH))

Bindungsspezifität: AA 37-175

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTHLH Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Parathyroid hormone-related protein (37-175AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PTHLH

Target: PTHLH (Parathyroid Hormone-Like Hormone (PTHLH))

Andere Bezeichnung: PTHLH (PTHLH Produkte)

Synonyme: BDE2 antikoerper, HHM antikoerper, PLP antikoerper, PTHR antikoerper, PTHRP antikoerper, PTHrP antikoerper, PTHLH antikoerper, pthlh antikoerper, pthrp antikoerper, si:ch211-286m4.5 antikoerper, PTH-like antikoerper, Pthrp antikoerper, PTHR1 antikoerper, parathyroid hormone like hormone antikoerper, parathyroid hormone-like hormone antikoerper, parathyroid hormone-like hormone a antikoerper, parathyroid hormone-like hormone L homeolog antikoerper, parathyroid hormone-like peptide antikoerper, parathyroid hormone 1 receptor antikoerper, PTHLH antikoerper, Pthlh antikoerper, pthlha antikoerper, pthlh.L antikoerper, PTH1R antikoerper

Hintergrund:

Background: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath By similarity. Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner through activation of Rac1.

Aliases: HHM antibody, MGC14611 antibody, Osteostatin antibody, Parathyroid hormon like hormone isoform 2 preproprotein antibody, Parathyroid hormone like hormone antibody, Parathyroid hormone like hormone isoform 1 preproprotein antibody, Parathyroid hormone like protein antibody, Parathyroid hormone like related protein antibody, Parathyroid hormone related protein antibody, Parathyroid hormone-like protein antibody, Parathyroid like protein antibody, PLP antibody, PTH related protein antibody, PTH-rP antibody, PTHLH antibody, PTHR antibody, PTHR_HUMAN antibody, PTHrP antibody, PTHrP[107-139] antibody

UniProt: P12272

Pathways: Hormone Activity, cAMP Metabolic Process