PIK3C3 Antikörper (pSer164)

Produktnummer ABIN711686

Produktdetails anti-PIK3C3 Antikörper

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Bindungsspezifität: pSer164

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3C3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PIK3C3 around the phosphorylation site of Ser164

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PIK3C3 Antikörper (ABIN711686)

Wang, Liang, Lau, Du, Guo, Yan, Gan, Yan, Zhao, Gao, Koch, Ma: "Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling." in: Autophagy, Vol. 13, Issue 11, pp. 1855-1869, (2017) (PubMed).

Details zu PIK3C3

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Andere Bezeichnung: Pik3c3 (PIK3C3 Produkte)

Synonyme: im:7147158 antikoerper, wu:fc13g06 antikoerper, wu:fz51e12 antikoerper, zgc:112016 antikoerper, zgc:113009 antikoerper, VPS34 antikoerper, hVps34 antikoerper, 5330434F23Rik antikoerper, Vps34 antikoerper, phosphatidylinositol 3-kinase catalytic subunit type 3 antikoerper, phosphatidylinositol 3-kinase catalytic subunit type 3 L homeolog antikoerper, phosphatidylinositol 3-kinase, catalytic subunit type 3 antikoerper, PIK3C3 antikoerper, pik3c3.L antikoerper, pik3c3 antikoerper, Pik3c3 antikoerper

Hintergrund:

Synonyms: VPS34, hVps34, Phosphatidylinositol 3-kinase catalytic subunit type 3, PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, PIK3C3

Background: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.

Gen-ID: 5289

UniProt: Q8NEB9

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagie