KPNA2 Antikörper (AA 2-285) (HRP)

Produktnummer ABIN7156121

Produktdetails anti-KPNA2 Antikörper (HRP)

Target: KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))

Bindungsspezifität: AA 2-285

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Importin subunit alpha-1 protein (2-285AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KPNA2

Target: KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))

Andere Bezeichnung: KPNA2 (KPNA2 Produkte)

Synonyme: IPOA1 antikoerper, QIP2 antikoerper, RCH1 antikoerper, SRP1alpha antikoerper, ima2 antikoerper, importin antikoerper, 2410044B12Rik antikoerper, PTAC58 antikoerper, Rch1 antikoerper, ipoa1 antikoerper, kpna2 antikoerper, qip2 antikoerper, rch1 antikoerper, srp1alpha antikoerper, hm:zeh0389 antikoerper, hm:zeh0389r antikoerper, zgc:113902 antikoerper, zgc:86945 antikoerper, karyopherin subunit alpha 2 antikoerper, importin subunit alpha-2 antikoerper, Importin subunit alpha-2 antikoerper, karyopherin (importin) alpha 2 antikoerper, karyopherin alpha-2 subunit like L homeolog antikoerper, karyopherin alpha 2 (RAG cohort 1, importin alpha 1) antikoerper, KPNA2 antikoerper, EDI_246290 antikoerper, EDI_335040 antikoerper, ima2 antikoerper, Kpna2 antikoerper, kpna2.L antikoerper, kpna2 antikoerper

Hintergrund:

Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

Aliases: IMA1_HUMAN antibody, Importin alpha 1 antibody, Importin alpha 2 antibody, Importin alpha 2 subunit antibody, Importin alpha P1 antibody, Importin subunit alpha-1 antibody, IPO A1 antibody, IPOA 1 antibody, IPOA1 antibody, Karyopherin alpha 2 antibody, Karyopherin alpha 2 RAG cohort 1 antibody, Karyopherin alpha 2 subunit antibody, Karyopherin subunit alpha-2 antibody, KPNA2 antibody, KPNA2 protein antibody, Pendulin antibody, QIP 2 antibody, QIP2 antibody, RAG cohort 1 antibody, RAG cohort protein 1 antibody, RCH 1 antibody, RCH1 antibody, SRP 1 antibody, SRP1 alpha antibody, SRP1 antibody, SRP1-alpha antibody, SRP1alpha antibody

UniProt: P52292

Pathways: M Phase, Protein targeting to Nucleus