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CHAC1 Antikörper (AA 43-264) (Biotin)

CHAC1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7154131
  • Target Alle CHAC1 Antikörper anzeigen
    CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
    Bindungsspezifität
    • 16
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 43-264
    Reaktivität
    • 29
    • 20
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 27
    • 3
    Kaninchen
    Klonalität
    • 27
    • 3
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHAC1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 25
    • 14
    • 13
    • 13
    • 8
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Glutathione-specific gamma-glutamylcyclotransferase 1 protein (43-264AA)
    Isotyp
    IgG
    Top Product
    Discover our top product CHAC1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
    Andere Bezeichnung
    CHAC1 (CHAC1 Produkte)
    Synonyme
    1810008K03Rik antikoerper, RGD1307153 antikoerper, ChaC glutathione specific gamma-glutamylcyclotransferase 1 antikoerper, ChaC, cation transport regulator 1 antikoerper, ChaC glutathione-specific gamma-glutamylcyclotransferase 1 antikoerper, CHAC1 antikoerper, Chac1 antikoerper
    Hintergrund

    Background: Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution (PubMed:23070364). Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178). Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).

    Aliases: Blocks Notch protein antibody, Botch antibody, Cation transport regulator like protein 1 antibody, Cation transport regulator-like protein 1 antibody, ChaC antibody, ChaC cation transport regulator homolog 1 antibody, ChaC cation transport regulator like 1 antibody, chac1 antibody, CHAC1_HUMAN antibody, Gamma GCT acting on glutathione homolog 1 antibody, Gamma-GCG 1 antibody, Glutathione-specific gamma-glutamylcyclotransferase 1 antibody

    UniProt
    Q9BUX1
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