APH1A Antikörper (AA 90-118)

Produktnummer ABIN7153559

Produktdetails anti-APH1A Antikörper

Target: APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))

Bindungsspezifität: AA 90-118

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APH1A Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Gamma-secretase subunit APH-1A protein (90-118AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu APH1A

Target: APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))

Andere Bezeichnung: APH1A (APH1A Produkte)

Synonyme: 6530402N02Rik antikoerper, APH-1 antikoerper, APH-1A antikoerper, CGI-78 antikoerper, RGD1311546 antikoerper, APH-1a antikoerper, aph-1 homolog A, gamma-secretase subunit antikoerper, aph-1 homolog A, gamma secretase subunit L homeolog antikoerper, aph-1 homolog A, gamma secretase subunit antikoerper, anterior pharynx defective 1 homolog A (C. elegans) antikoerper, aph1 homolog A, gamma secretase subunit antikoerper, acylamino-acid-releasing enzyme-like antikoerper, APH1A antikoerper, aph1a.L antikoerper, Aph1a antikoerper, LOC100219182 antikoerper

Hintergrund:

Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.

Aliases: 6530402N02Rik antibody, AL138795.3 antibody, Anterior Pharynx Defective 1 antibody, Anterior pharynx defective 1 homolog A antibody, APH 1A antibody, Aph 1alpha antibody, APH-1a antibody, Aph-1alpha antibody, Aph1a antibody, APH1A gamma secretase subunit antibody, APH1A_HUMAN antibody, CGI 78 antibody, CGI78 antibody, Gamma secretase subunit APH 1A antibody, Gamma Secretase Subunit APH1a antibody, Gamma-secretase subunit APH-1A antibody, Likely ortholog of C. elegans anterior pharynx defective 1A antibody, Presenilin Stabilization Factor antibody, Presenilin-stabilization factor antibody, PSF antibody, UNQ579/PRO1141 antibody

UniProt: Q96BI3

Pathways: Notch Signalweg, Neurotrophin Signalübertragung