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POLR3E Antikörper (AA 1-260) (Biotin)

POLR3E Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7150463
  • Target Alle POLR3E Antikörper anzeigen
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    Bindungsspezifität
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260
    Reaktivität
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 21
    • 2
    Kaninchen
    Klonalität
    • 21
    • 2
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLR3E Antikörper ist konjugiert mit Biotin
    Applikation
    • 9
    • 9
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
    Isotyp
    IgG
    Top Product
    Discover our top product POLR3E Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    Andere Bezeichnung
    POLR3E (POLR3E Produkte)
    Synonyme
    RPC5 antikoerper, SIN antikoerper, Sin antikoerper, MGC78924 antikoerper, RGD1308086 antikoerper, wu:fb12d10 antikoerper, wu:fs42e03 antikoerper, zgc:55592 antikoerper, RNA polymerase III subunit E antikoerper, polymerase (RNA) III (DNA directed) polypeptide E antikoerper, polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog antikoerper, polymerase (RNA) III (DNA directed) polypeptide E (80kD) antikoerper, DNA-directed RNA polymerase III subunit RPC5 antikoerper, POLR3E antikoerper, Polr3e antikoerper, polr3e.L antikoerper, polr3e antikoerper, LOC608689 antikoerper
    Hintergrund

    Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

    Aliases: POLR3E antibody, KIAA1452 antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, RNA polymerase III subunit C5 antibody, DNA-directed RNA polymerase III 80 kDa polypeptide antibody

    UniProt
    Q9NVU0
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