PRKACB Antikörper (Catalytic Subunit beta)

Produktnummer ABIN7146602

Produktdetails anti-PRKACB Antikörper

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Bindungsspezifität: AA 2-53, Catalytic Subunit beta

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKACB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human cAMP-dependent protein kinase catalytic subunit beta protein (2-53AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PRKACB

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Andere Bezeichnung: PRKACB (PRKACB Produkte)

Synonyme: PKACB antikoerper, XPKAbeta antikoerper, kin-1 antikoerper, pkacb antikoerper, prkacba antikoerper, PRKACB antikoerper, prkacb antikoerper, wu:fz54b03 antikoerper, zgc:110804 antikoerper, Pkacb antikoerper, protein kinase cAMP-activated catalytic subunit beta antikoerper, protein kinase cAMP-activated catalytic subunit beta S homeolog antikoerper, protein kinase, cAMP-dependent, catalytic, beta antikoerper, protein kinase, cAMP-dependent, catalytic, beta b antikoerper, protein kinase, cAMP dependent, catalytic, beta antikoerper, PRKACB antikoerper, prkacb.S antikoerper, prkacb antikoerper, Prkacb antikoerper, prkacbb antikoerper

Hintergrund:

Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Aliases: cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody, cAMP-dependent protein kinase catalytic subunit beta antibody, KAPCB_HUMAN antibody, PKA C beta antibody, PKA C-beta antibody, PKACB antibody, Prkacb antibody, protein kinase A catalytic subunit beta antibody, Protein kinase cAMP dependent catalytic beta antibody

UniProt: P22694

Pathways: AMPK Signaling, Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism