Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MST1R Antikörper (pTyr1238)

MST1R Reaktivität: Human, Maus, Ratte, Affe WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN710336
  • Target Alle MST1R Antikörper anzeigen
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    Bindungsspezifität
    • 40
    • 21
    • 14
    • 12
    • 11
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1238
    Reaktivität
    • 98
    • 61
    • 40
    • 5
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Affe
    Wirt
    • 109
    • 3
    • 2
    Kaninchen
    Klonalität
    • 103
    • 11
    Polyklonal
    Konjugat
    • 38
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser MST1R Antikörper ist unkonjugiert
    Applikation
    • 81
    • 35
    • 23
    • 21
    • 17
    • 15
    • 15
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Affe, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1238
    Isotyp
    IgG
    Top Product
    Discover our top product MST1R Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    Andere Bezeichnung
    Ron (MST1R Produkte)
    Synonyme
    CD136 antikoerper, CDw136 antikoerper, PTK8 antikoerper, RON antikoerper, Fv-2 antikoerper, Fv2 antikoerper, Ron antikoerper, STK antikoerper, Cdw136 antikoerper, Ptk8 antikoerper, Stk antikoerper, macrophage stimulating 1 receptor antikoerper, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antikoerper, MST1R antikoerper, Mst1r antikoerper
    Hintergrund

    Synonyms: RON, PTK8, CD136, CDw136, Macrophage-stimulating protein receptor, MSP receptor, Protein-tyrosine kinase 8, p185-Ron, MST1R

    Background: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.

    Gen-ID
    4486
    UniProt
    Q04912
    Pathways
    RTK Signalweg
Sie sind hier:
Kundenservice