Kir2.2 Antikörper (AA 182-433) (Biotin)

Produktnummer ABIN7145026

Produktdetails anti-Kir2.2 Antikörper (Biotin)

Target: Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))

Bindungsspezifität: AA 182-433

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kir2.2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ATP-sensitive inward rectifier potassium channel 12 protein (182-433aa)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Kir2.2

Target: Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))

Andere Bezeichnung: KCNJ12 (KCNJ12 Produkte)

Synonyme: IRK-2 antikoerper, IRK2 antikoerper, KCNJN1 antikoerper, Kir2.2 antikoerper, Kir2.2v antikoerper, hIRK antikoerper, hIRK1 antikoerper, hkir2.2x antikoerper, kcnj12x antikoerper, Kir2.1 antikoerper, IRK antikoerper, KIR2.2 antikoerper, MB-IRK2 antikoerper, potassium voltage-gated channel subfamily J member 12 antikoerper, ATP-sensitive inward rectifier potassium channel 12 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 12 antikoerper, KCNJ12 antikoerper, LOC746628 antikoerper, Kcnj12 antikoerper

Hintergrund:

Background: Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Aliases: ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12), KCNJ12, IRK2 KCNJN1

UniProt: Q14500