ABCG2 Antikörper (AA 296-371) (Biotin)

Produktnummer ABIN7372523

Produktdetails anti-ABCG2 Antikörper (Biotin)

Target: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Bindungsspezifität: AA 296-371

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCG2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ATP-binding cassette sub-family G member 2 protein (296-371AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ABCG2

Target: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Andere Bezeichnung: ABCG2 (ABCG2 Produkte)

Synonyme: bcrp antikoerper, ABCG2 antikoerper, ABC15 antikoerper, ABCP antikoerper, BCRP antikoerper, BCRP1 antikoerper, BMDP antikoerper, CD338 antikoerper, CDw338 antikoerper, EST157481 antikoerper, GOUT1 antikoerper, MRX antikoerper, MXR antikoerper, MXR1 antikoerper, UAQTL1 antikoerper, AI428558 antikoerper, Bcrp1 antikoerper, ABCG3 antikoerper, ATP binding cassette subfamily G member 2 antikoerper, ATP binding cassette subfamily G member 2 (Junior blood group) antikoerper, ATP binding cassette subfamily G member 2 (Junior blood group) L homeolog antikoerper, ATP-binding cassette, sub-family G (WHITE), member 2 antikoerper, ATP-binding cassette sub-family G member 2 antikoerper, ABCG2 antikoerper, abcg2 antikoerper, abcg2.L antikoerper, Abcg2 antikoerper, LOC100008640 antikoerper

Hintergrund:

Background: High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.

Aliases: ABC transporter antibody, ABC15 antibody, ABCG 2 antibody, ABCG2 antibody, ABCG2_HUMAN antibody, ABCP antibody, ATP binding cassette sub family G (WHITE) member 2 antibody, ATP binding cassette transporter G2 antibody, ATP-binding cassette sub-family G member 2 antibody, BCRP antibody, BCRP1 antibody, BMDP antibody, Breast cancer resistance protein antibody, CD338 antibody, CDw338 antibody, CDw338 antigen antibody, EST157481 antibody, GOUT1 antibody, MGC102821 antibody, Mitoxantrone resistance associated protein antibody, Mitoxantrone resistance-associated protein antibody, MRX antibody, Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody, MXR antibody, MXR1 antibody, Placenta specific ATP binding cassette transporter antibody, Placenta specific MDR protein antibody, Placenta-specific ATP-binding cassette transporter antibody, UAQTL1 antibody

UniProt: Q9UNQ0

Pathways: Transition Metal Ion Homeostasis