NUDT1 Antikörper (AA 49-82) (FITC)

Produktnummer ABIN7142860

Produktdetails anti-NUDT1 Antikörper (FITC)

Target: NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))

Bindungsspezifität: AA 49-82

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUDT1 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human 7,8-dihydro-8-oxoguanine triphosphatase protein (49-82AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NUDT1

Target: NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))

Andere Bezeichnung: NUDT1 (NUDT1 Produkte)

Synonyme: mutT antikoerper, nudT1 antikoerper, MTH1 antikoerper, Mth1 antikoerper, 7,8-dihydro-8-oxoguanine triphosphatase antikoerper, nudix hydrolase 1 antikoerper, nudix (nucleoside diphosphate linked moiety X)-type motif 1 antikoerper, mth1 antikoerper, Tsp_07498 antikoerper, nudt1 antikoerper, 8odp antikoerper, NUDT1 antikoerper, Nudt1 antikoerper

Hintergrund:

Background: Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.

Aliases: 2-hydroxy-dATP diphosphatase antibody, 7 8 dihydro 8 oxoguanine triphosphatase antibody, 7 antibody, 8 oxo 7 8 dihydrodeoxyguanosine triphosphatase antibody, 8 oxo 7 8 dihydroguanosine triphosphatase antibody, 8 oxo dGTPase antibody, 8-dihydro-8-oxoguanine triphosphatase antibody, 8-oxo-dGTPase antibody, 8ODP_HUMAN antibody, MTH 1 antibody, MTH1 antibody, MutT human homolog 1 antibody, Nucleoside diphosphate linked moiety X motif 1 antibody, Nucleoside diphosphate linked moiety X type motif 1 antibody, Nucleoside diphosphate-linked moiety X motif 1 antibody, Nudix (nucleoside diphosphate linked moiety X) type motif 1 antibody, Nudix hydrolase 1 antibody, Nudix motif 1 antibody, Nudix type motif 1 antibody, NUDT 1 antibody, Nudt1 antibody

UniProt: P36639