FZD7 Antikörper (AA 501-574) (HRP)

Produktnummer ABIN710060

Produktdetails anti-FZD7 Antikörper (HRP)

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Bindungsspezifität: AA 501-574

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD7 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Frizzled 7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FZD7

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Andere Bezeichnung: Frizzled 7 (FZD7 Produkte)

Synonyme: FzE3 antikoerper, Fz-7 antikoerper, Xfz7 antikoerper, frizzled-7 antikoerper, frizzled7 antikoerper, frz-7 antikoerper, frz7 antikoerper, fz7 antikoerper, fzd7-a antikoerper, fzd7-b antikoerper, fze3 antikoerper, Fz7 antikoerper, cFz-7 antikoerper, fb38g02 antikoerper, fc44b09 antikoerper, fz13 antikoerper, fz7a antikoerper, fz7b antikoerper, wu:fb38g02 antikoerper, wu:fc44b09 antikoerper, zg13 antikoerper, frizzled class receptor 7 antikoerper, frizzled class receptor 7 L homeolog antikoerper, frizzled class receptor 7b antikoerper, FZD7 antikoerper, fzd7.L antikoerper, fzd7 antikoerper, Fzd7 antikoerper, fzd7b antikoerper

Hintergrund:

Synonyms: FzE3, Frizzled-7, Fz-7, hFz7, FZD7

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Gen-ID: 8324

UniProt: O75084

Pathways: WNT Signalweg, Stem Cell Maintenance