SLC3A2 Antikörper (AA 404-630)

Produktnummer ABIN7142591

Produktdetails anti-SLC3A2 Antikörper

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Bindungsspezifität: AA 404-630

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC3A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human 4F2 cell-surface antigen heavy chain protein (404-630AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SLC3A2

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Andere Bezeichnung: SLC3A2 (SLC3A2 Produkte)

Synonyme: 4F2 antikoerper, 4F2HC antikoerper, 4T2HC antikoerper, CD98 antikoerper, CD98HC antikoerper, MDU1 antikoerper, NACAE antikoerper, Mdu1 antikoerper, MGC53951 antikoerper, slc3a2 antikoerper, MGC53965 antikoerper, SLC3A2 antikoerper, AI314110 antikoerper, Cd98 antikoerper, Ly-10 antikoerper, Ly-m10 antikoerper, Ly10 antikoerper, Mgp-2hc antikoerper, fc65h12 antikoerper, wu:fc65h12 antikoerper, id:ibd1327 antikoerper, sb:cb519 antikoerper, wu:fe14a07 antikoerper, wu:fq18d12 antikoerper, zgc:55813 antikoerper, solute carrier family 3 member 2 antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog antikoerper, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2a antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2b antikoerper, SLC3A2 antikoerper, Slc3a2 antikoerper, slc3a2.L antikoerper, slc3a2.S antikoerper, slc3a2a antikoerper, slc3a2b antikoerper

Hintergrund:

Background: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.

Aliases: 4F2 antibody, 4F2 cell surface antigen heavy chain antibody, 4F2 cell-surface antigen heavy chain antibody, 4F2 heavy chain antibody, 4F2 heavy chain antigen antibody, 4F2_HUMAN antibody, 4F2hc antibody, 4T2HC antibody, Antigen defined by monoclonal antibody 4F2 heavy chain antibody, Antigen identified by monoclonal antibodies 4F2 TRA1.10 TROP4 and T43 antibody, CD 98 antibody, CD98 antibody, CD98 antigen antibody, CD98 heavy chain antibody, CD98HC antibody, Heavy chain antibody, Lymphocyte activation antigen 4F2 large subunit antibody, MDU 1 antibody, MDU1 antibody, Monoclonal antibody 44D7 antibody, NACAE antibody, Slc3a2 antibody, Solute carrier family 3 (activators of dibasic and neutral amino acid transport) member 2 antibody, Solute carrier family 3 member 2 antibody

UniProt: P08195