PKC delta Antikörper (pSer645)

Produktnummer ABIN7138674

Produktdetails anti-PKC delta Antikörper

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Bindungsspezifität: pSer645

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC delta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 645 (R-L-S(p)-Y-S) derived from Human PKCd.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PKC delta

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Andere Bezeichnung: PRKCD (PKCd Produkte)

Synonyme: MAY1 antikoerper, PKCD antikoerper, nPKC-delta antikoerper, AI385711 antikoerper, D14Ertd420e antikoerper, PKC[d] antikoerper, PKCdelta antikoerper, Pkcd antikoerper, fb09d10 antikoerper, fv43b11 antikoerper, prkcd antikoerper, wu:fb09d10 antikoerper, wu:fv43b11 antikoerper, zgc:56558 antikoerper, PKC-delta antikoerper, may1 antikoerper, npkc-delta antikoerper, pkc-delta2 antikoerper, pkcd antikoerper, tpa-1 antikoerper, protein kinase C delta antikoerper, protein kinase C, delta antikoerper, protein kinase C, delta a antikoerper, protein kinase C delta L homeolog antikoerper, PRKCD antikoerper, Prkcd antikoerper, prkcda antikoerper, prkcd.L antikoerper, prkcd antikoerper

Hintergrund:

Background: This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

Kei Sakamoto, et,al. (2003) Am J Physiol Endocrinol Metab , 285: E1081 - E1088.
Ling Zhang, et,al. (2004) J. Biol. Chem , 279: 28315 - 28319.
Kristof Van Kolen et,al. (2006) FEBS J , 273: 1843 - 1854.
Martin Villalba, et,al. (2002) J. Cell Biol , 157: 253.

Aliases: CVID9 antibody, D14Ertd420e antibody, Kinase PKC delta antibody, KPCD antibody, KPCD_HUMAN antibody, MAY 1 antibody, MAY1 antibody, MGC49908 antibody, nPKC delta antibody, nPKC-delta antibody, PCKd antibody, PKC d antibody, PKC delta antibody, PKCD antibody, PKCdelta antibody, PRKC D antibody, PRKC delta antibody, Prkcd antibody, Protein Kinase C delta antibody, Protein kinase C delta type antibody, Protein kinase C delta VIII antibody, Protein Kinase Cdelta antibody, Tyrosine protein kinase PRKCD antibody

UniProt: Q05655

Pathways: Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism