ERCC1 Antikörper (AA 1-200)
Kurzübersicht für ERCC1 Antikörper (AA 1-200) (ABIN7113986)
Target
Alle ERCC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-200
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Verwendungszweck
- ERCC1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1-200aa
Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 1(includes overlapping antisense sequence)
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
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Andere Bezeichnung
- ERCC1
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Hintergrund
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Synonyms: DNA excision repair protein ERCC-1|ERCC1
Background: Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links(ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair(HDR) of DNA double-strand breaks, in conjunction with SLX4.
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Molekulargewicht
- 36-38 kDa
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Gen-ID
- 2067
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UniProt
- P07992
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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