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APH1A Antikörper (AA 71-170)

APH1A Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN706016
  • Target Alle APH1A Antikörper anzeigen
    APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
    Bindungsspezifität
    • 15
    • 14
    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 71-170
    Reaktivität
    • 54
    • 34
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 59
    • 1
    Kaninchen
    Klonalität
    • 60
    Polyklonal
    Konjugat
    • 20
    • 7
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APH1A Antikörper ist unkonjugiert
    Applikation
    • 51
    • 36
    • 14
    • 13
    • 12
    • 12
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human APH1a
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
    Andere Bezeichnung
    APH1a (APH1A Produkte)
    Synonyme
    6530402N02Rik antikoerper, APH-1 antikoerper, APH-1A antikoerper, CGI-78 antikoerper, RGD1311546 antikoerper, APH-1a antikoerper, aph-1 homolog A, gamma-secretase subunit antikoerper, aph-1 homolog A, gamma secretase subunit L homeolog antikoerper, aph-1 homolog A, gamma secretase subunit antikoerper, anterior pharynx defective 1 homolog A (C. elegans) antikoerper, aph1 homolog A, gamma secretase subunit antikoerper, acylamino-acid-releasing enzyme-like antikoerper, APH1A antikoerper, aph1a.L antikoerper, Aph1a antikoerper, LOC100219182 antikoerper
    Hintergrund

    Synonyms: APH-1, APH-1A, CGI-78, 6530402N02Rik, Gamma-secretase subunit APH-1A, Aph-1alpha, Presenilin-stabilization factor, APH1A, PSF, UNQ579/PRO1141

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.

    Gen-ID
    51107
    UniProt
    Q96BI3
    Pathways
    Notch Signalweg, Neurotrophin Signalübertragung
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