TFG Antikörper

Produktnummer ABIN7076022

Produktdetails anti-TFG Antikörper

Target: TFG (Trk-Fused Gene (TFG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Human TRK fused gene

Anwendungsinformationen

Applikationshinweise: WB (H) 1:500- 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TFG

Target: TFG (Trk-Fused Gene (TFG))

Andere Bezeichnung: TRK fused gene (TFG Produkte)

Synonyme: wu:fb11c10 antikoerper, zgc:55342 antikoerper, zgc:77230 antikoerper, HMSNP antikoerper, SPG57 antikoerper, TF6 antikoerper, TRKT3 antikoerper, AI173908 antikoerper, trk-fused gene antikoerper, TRK-fused gene antikoerper, Trk-fused gene antikoerper, tfg antikoerper, TFG antikoerper, Tfg antikoerper

Hintergrund: Protein TFG (TRK-fused gene protein) plays a role in regulating phosphotyrosine-specific phosphatase-1 activity. Mutations in TFG may have important clinical relevance for current therapeutic strategies to treat metastatic melanoma. Defects in TFG are a cause of thyroid papillary carcinoma (TPC), a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Recent genetic investigation indicates that formation of TFG-containing cytoplasmic inclusions and concomitant mislocalization of TAR DNA-binding protein 43 kDa (TDP-43) underlie motor neuron degeneration in HMSN-P. Pathological overlap of proteinopathies involving TFG and TDP-43 highlights a new pathway leading to motor neuron degeneration.

Molekulargewicht: 55 kDa

Gen-ID: 10342

UniProt: Q92734