TBC1D17 Antikörper

Produktnummer ABIN7075844

Produktdetails anti-TBC1D17 Antikörper

Target: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TBC1D17

Anwendungsinformationen

Applikationshinweise: WB (H,R) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TBC1D17

Target: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Andere Bezeichnung: TBC1D17 (TBC1D17 Produkte)

Synonyme: BC017607 antikoerper, TBC1 domain family member 17 antikoerper, TBC1 domain family, member 17 antikoerper, TBC1D17 antikoerper, Tbc1d17 antikoerper

Hintergrund: Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.

Molekulargewicht: 73 kDa

Gen-ID: 233204

NCBI Accession: NP_001036120

UniProt: Q8BYH7