SPATA13 Antikörper

Produktnummer ABIN7075700

Produktdetails anti-SPATA13 Antikörper

Target: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPATA13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Asef2

Anwendungsinformationen

Applikationshinweise: WB (H) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SPATA13

Target: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Andere Bezeichnung: Asef2 (SPATA13 Produkte)

Synonyme: ARHGEF29 antikoerper, ASEF2 antikoerper, C79050 antikoerper, ESTM11 antikoerper, X83327 antikoerper, mFLJ00298 antikoerper, spermatogenesis associated 13 antikoerper, SPATA13 antikoerper, Spata13 antikoerper

Hintergrund: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Molekulargewicht: 75 kDa

Gen-ID: 219140

NCBI Accession: NP_001028444

UniProt: Q5DU57