POLR3D Antikörper

Produktnummer ABIN7075141

Produktdetails anti-POLR3D Antikörper

Target: POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR3D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse POLR3D

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu POLR3D

Target: POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))

Andere Bezeichnung: POLR3D (POLR3D Produkte)

Synonyme: 2810426M17Rik antikoerper, 44kDa antikoerper, AI326118 antikoerper, AW489084 antikoerper, BN51T antikoerper, RPC4 antikoerper, TSBN51 antikoerper, RPC53 antikoerper, RNA polymerase III subunit D antikoerper, polymerase (RNA) III (DNA directed) polypeptide D antikoerper, Polr3d antikoerper, POLR3D antikoerper

Hintergrund: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway .

Molekulargewicht: 55 kDa

Gen-ID: 67065

NCBI Accession: NP_001157554

UniProt: Q91WD1