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NOTCH4 Antikörper

NOTCH4 Reaktivität: Human IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074863
  • Target Alle NOTCH4 Antikörper anzeigen
    NOTCH4 (Notch 4 (NOTCH4))
    Reaktivität
    • 44
    • 31
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 55
    • 3
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 49
    • 16
    Polyklonal
    Konjugat
    • 33
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NOTCH4 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 17
    • 13
    • 13
    • 8
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse NOTCH4
    Top Product
    Discover our top product NOTCH4 Primärantikörper
  • Applikationshinweise
    IHC/IF (H) 1:600-1:1200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    NOTCH4 (Notch 4 (NOTCH4))
    Andere Bezeichnung
    Notch4 (NOTCH4 Produkte)
    Synonyme
    INT3 antikoerper, NOTCH3 antikoerper, Int-3 antikoerper, Int3 antikoerper, N4 antikoerper, Notch4 antikoerper, notch 4 antikoerper, neurogenic locus notch homolog protein 4 antikoerper, NOTCH4 antikoerper, Notch4 antikoerper, LOC100712850 antikoerper
    Hintergrund
    Notch4 is a member of the Notch family. The Notch4 signaling network is an evolutionarily conserved intracellular pathway that regulates physical cell to cell interactions. The Notch4 protein, once cleaved from the trans-Golgi network, is presented on the cell surface as a heterodimer. Notch4 regulates cell-fate determination as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1. In Drosophila, once these ligands are activated via the release of the notch intracellular domain (NICD), Notch4 forms a transcriptional activator complex with RBPJ/RBPSUH which then activates the genes of the Enhancer of Split (E(spl)) locus. Notch4 also plays a role in vascular, renal and hepatic development, the implementation of differentiation, proliferation and apoptotic programs, and the regulation of branching morphogenesis in the development of the vascular system.
    Gen-ID
    18132
    NCBI Accession
    NP_035059
    UniProt
    P31695
    Pathways
    Notch Signalweg
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