NOTCH4 Antikörper
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- Target Alle NOTCH4 Antikörper anzeigen
- NOTCH4 (Notch 4 (NOTCH4))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NOTCH4 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse NOTCH4
- Top Product
- Discover our top product NOTCH4 Primärantikörper
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- Applikationshinweise
- IHC/IF (H) 1:600-1:1200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- NOTCH4 (Notch 4 (NOTCH4))
- Andere Bezeichnung
- Notch4 (NOTCH4 Produkte)
- Synonyme
- INT3 antikoerper, NOTCH3 antikoerper, Int-3 antikoerper, Int3 antikoerper, N4 antikoerper, Notch4 antikoerper, notch 4 antikoerper, neurogenic locus notch homolog protein 4 antikoerper, NOTCH4 antikoerper, Notch4 antikoerper, LOC100712850 antikoerper
- Hintergrund
- Notch4 is a member of the Notch family. The Notch4 signaling network is an evolutionarily conserved intracellular pathway that regulates physical cell to cell interactions. The Notch4 protein, once cleaved from the trans-Golgi network, is presented on the cell surface as a heterodimer. Notch4 regulates cell-fate determination as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1. In Drosophila, once these ligands are activated via the release of the notch intracellular domain (NICD), Notch4 forms a transcriptional activator complex with RBPJ/RBPSUH which then activates the genes of the Enhancer of Split (E(spl)) locus. Notch4 also plays a role in vascular, renal and hepatic development, the implementation of differentiation, proliferation and apoptotic programs, and the regulation of branching morphogenesis in the development of the vascular system.
- Gen-ID
- 18132
- NCBI Accession
- NP_035059
- UniProt
- P31695
- Pathways
- Notch Signalweg
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