FBXW4 Antikörper
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- Target Alle FBXW4 Antikörper anzeigen
- FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FBXW4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse FBXW4
- Top Product
- Discover our top product FBXW4 Primärantikörper
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- Applikationshinweise
- WB (M,R) 1:1000-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
- Andere Bezeichnung
- FBXW4 (FBXW4 Produkte)
- Synonyme
- dac antikoerper, hag antikoerper, hagoromo antikoerper, wu:fk63g06 antikoerper, FBXW4 antikoerper, DAC antikoerper, FBW4 antikoerper, FBWD4 antikoerper, SHFM3 antikoerper, SHSF3 antikoerper, Dac antikoerper, Fbw4 antikoerper, dactylin antikoerper, dactylyn antikoerper, F-box and WD repeat domain containing 4 antikoerper, F-box and WD-40 domain protein 4 antikoerper, fbxw4 antikoerper, FBXW4 antikoerper, Fbxw4 antikoerper
- Hintergrund
- F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. FBXW4, also known as SHFM3, encodes F-box and WD-40 domain-containing protein 4. Defects in SHFM3 are a cause of split-hand/foot malformation type 3 (SHFM3), an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.
- Molekulargewicht
- 46 kDa
- Gen-ID
- 30838
- NCBI Accession
- NP_038935
- UniProt
- Q9JMJ2
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