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alpha Actinin Antikörper

ACTN Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7073024
  • Target Alle alpha Actinin (ACTN) Antikörper anzeigen
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    Reaktivität
    • 11
    • 9
    • 9
    • 3
    • 1
    Human, Maus, Ratte
    Wirt
    • 8
    • 3
    Kaninchen
    Klonalität
    • 8
    • 3
    Polyklonal
    Konjugat
    • 7
    • 2
    • 2
    Dieser alpha Actinin Antikörper ist unkonjugiert
    Applikation
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse alpha-actinin1
    Top Product
    Discover our top product ACTN Primärantikörper
  • Applikationshinweise
    WB (H,M,R) 1:2000-1:4000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    Andere Bezeichnung
    alpha Actinin (ACTN Produkte)
    Synonyme
    actinin, alpha 4 antikoerper, alpha-actinin antikoerper, ACTN4 antikoerper, ain1 antikoerper
    Hintergrund
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found alongmicrofilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.
    Molekulargewicht
    103 kDa
    Gen-ID
    109711
    NCBI Accession
    NP_598917
    UniProt
    Q7TPR4
    Pathways
    Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
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