KCNG1 Antikörper (Extracellular)

Produktnummer ABIN7043541

Der Kaninchen Polyklonal anti-KCNG1 Antikörper (ABIN7043541) detektiert spezifisch KCNG1 in IHC, WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für KCNG1 Antikörper (Extracellular) (ABIN7043541)

Target: KCNG1 (Potassium Voltage-Gated Channel, Subfamily G, Member 1 (KCNG1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNG1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-KCNG1 Antikörper

Bindungsspezifität: AA 325-337, Extracellular

Verwendungszweck: A Rabbit Polyclonal Antibody to KCNG1 (KV6.1) Channel

Spezifität: 2nd extracellular loop

Kreuzreaktivität: Maus, Ratte

Homologie: Rat - identical, human - 11,13 amino acid residues identical

Produktmerkmale: Anti-KCNG1 (Kv6.1) (extracellular) Antibody is directed against an extracellular epitope of the mouse KV6.1 channel. Anti-KCNG1 (KV6.1) (extracellular) Antibody (ABIN7043541 and ABIN7045038) can be used in western blot and immunohistochemistry applications. It is specially suited for live cell imaging. It has been designed to recognize KV6.1 from rat, mouse and human samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RRKPSTGNSYLDK, corresponding to amino acid residues 325-337 of mouse KV6.1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

Application Dilutions Western blot wb: 1:400

Kommentare:

Negative Control: (ABIN7236551)

Blocking Peptide: (ABIN7236551)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu KCNG1

Target: KCNG1 (Potassium Voltage-Gated Channel, Subfamily G, Member 1 (KCNG1))

Andere Bezeichnung: KCNG1

Hintergrund: Potassium voltage-gated channel subfamily G member 1,Voltage-gated K+ channels are transmembrane proteins consisting of four α-subunits arranged in a radially symmetric fashion around a central aqueous pore. Each α-subunit consists of six transmembrane segments (S1-S6) with cytoplasmic NH2- and COOH-termini.In mammals, a large family of genes encodes α-subunits: KV1 (homologous to Drosophila Shaker), KV2 (Shab), KV3 (Shaw), KV4 (Shal), KV5, KV6, and KV91. The sparsely populated KV channel subfamilies KV5 and KV6 each contain one member, KV5.1 and KV6.12. KV6 channels are electrically silent and no functional role has been suggested for these channels3. A recent study found that KV6.1 forms functional channels specifically with KV2.13. It was also found that KV2.1 and KV6.1 mRNAs colocalize to the piriform cortex, hippocampus, dendate gyrus and olfactory tubercle in the brain4 and to SA node, atria and ventricle in the heart5. This suggests that KV6.1 may be physiologically important in generating an increased number of KV channel phenotypes even though it does not itself form functional homomultimeric channels3.

Alternative names: KCNG1 (KV6.1), Potassium voltage-gated channel subfamily G member 1

Gen-ID: 241794

NCBI Accession: NM_002237

UniProt: A2BDX4