SLC11A2 Antikörper (AA 251-350)

Produktnummer ABIN701065

Produktdetails anti-SLC11A2 Antikörper

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Bindungsspezifität: AA 251-350

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC11A2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Homologie: Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC11A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SLC11A2 Antikörper (ABIN701065)

Zhang, Li, Liao, Zhang, Lu, Luo: "Effect of iron source on iron absorption and gene expression of iron transporters in the ligated duodenal loops of broilers." in: Journal of animal science, Vol. 95, Issue 4, pp. 1587-1597, (2017) (PubMed).

Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).

Details zu SLC11A2

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Andere Bezeichnung: SLC11A2 (SLC11A2 Produkte)

Synonyme: DCT1 antikoerper, DMT1 antikoerper, NRAMP2 antikoerper, Nramp2 antikoerper, mk antikoerper, van antikoerper, Dmt1 antikoerper, ATNRAMP2 antikoerper, F8G22.4 antikoerper, F8G22_4 antikoerper, NRAMP metal ion transporter 2 antikoerper, dct1 antikoerper, dmt1 antikoerper, nramp2 antikoerper, SLC11A2 antikoerper, cb426 antikoerper, fa07b10 antikoerper, wu:fa07b10 antikoerper, zgc:136699 antikoerper, solute carrier family 11 member 2 antikoerper, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 antikoerper, NRAMP metal ion transporter 2 antikoerper, manganese transport protein antikoerper, metal transporter Nramp2 antikoerper, solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 antikoerper, SLC11A2 antikoerper, Slc11a2 antikoerper, NRAMP2 antikoerper, LOC9327403 antikoerper, slc11a2 antikoerper

Hintergrund:

Synonyms: DCT1, DMT1, NRAMP2, Natural resistance-associated macrophage protein 2, NRAMP 2, Divalent cation transporter 1, Divalent metal transporter 1, DMT-1, Solute carrier family 11 member 2, SLC11A2, OK/SW-cl.20

Background: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.

Gen-ID: 4891

UniProt: P49281

Pathways: Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity