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Geminin Antikörper

GMNN Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7261265
  • Target Alle Geminin (GMNN) Antikörper anzeigen
    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
    Reaktivität
    • 54
    • 11
    • 10
    Human
    Wirt
    • 48
    • 8
    Kaninchen
    Klonalität
    • 45
    • 11
    Polyklonal
    Konjugat
    • 31
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Geminin Antikörper ist unkonjugiert
    Applikation
    • 32
    • 25
    • 24
    • 13
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human GMNN (NP_056979.1).
    Isotyp
    IgG
    Top Product
    Discover our top product GMNN Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
    Andere Bezeichnung
    GMNN (GMNN Produkte)
    Synonyme
    CG3183 antikoerper, Dm Geminin antikoerper, Dm geminin antikoerper, Dmel\\CG3183 antikoerper, Gem antikoerper, Geminin antikoerper, anon-WO0257455.1 antikoerper, gem antikoerper, l(2)k14019 antikoerper, v(2)k09107 antikoerper, sb:cb254 antikoerper, zgc:66217 antikoerper, GB16871 antikoerper, GMNN antikoerper, geminin antikoerper, dyak_GLEANR_833 antikoerper, DyakGE24654 antikoerper, GE24654 antikoerper, LOC100049517 antikoerper, AW546347 antikoerper, geminin, DNA replication inhibitor antikoerper, CG3183 gene product from transcript CG3183-RA antikoerper, geminin antikoerper, GE24654 gene product from transcript GE24654-RA antikoerper, GMNN antikoerper, geminin antikoerper, gmnn antikoerper, LOC410093 antikoerper, Dyak\geminin antikoerper, Gmnn antikoerper
    Hintergrund
    This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
    Molekulargewicht

    Observed_MW: 24 kDa

    Calculated_MW: 23 kDa

    Gen-ID
    51053
    UniProt
    O75496
    Pathways
    EGFR Signaling Pathway, DNA Replication
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