MPG Antikörper

Produktnummer ABIN7009745

Produktdetails anti-MPG Antikörper

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody ist KO validated.

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Güteklasse: KO Validated

Immunogen: Recombinant fusion protein of human MPG (NP_001015052.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MPG

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Andere Bezeichnung: MPG (MPG Produkte)

Synonyme: AAG antikoerper, ADPG antikoerper, APNG antikoerper, CRA36.1 antikoerper, MDG antikoerper, Mid1 antikoerper, PIG11 antikoerper, PIG16 antikoerper, anpg antikoerper, 9830006D05 antikoerper, AI326268 antikoerper, Aag antikoerper, zgc:162984 antikoerper, si:xx-187g17.9 antikoerper, MPG antikoerper, MPGR antikoerper, N-methylpurine DNA glycosylase antikoerper, N-methylpurine-DNA glycosylase antikoerper, si:xx-by187g17.9 antikoerper, MPG antikoerper, Mpg antikoerper, mpg antikoerper, si:xx-by187g17.9 antikoerper, CpB0526 antikoerper, gll2491 antikoerper

Hintergrund: Maintenance of DNA sequences is necessary for vertebrates and other life. DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells. The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase). Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes. Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells. DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.

Molekulargewicht:

Observed_MW: 37 kDa

Calculated_MW: 30 kDa/32 kDa

Gen-ID: 4350

UniProt: P29372

Pathways: DNA Reparatur