GADD45A Antikörper

Produktnummer ABIN7255776

Produktdetails anti-GADD45A Antikörper

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GADD45A Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human GADD45A (NP_001915.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Andere Bezeichnung: GADD45A (GADD45A Produkte)

Synonyme: MGC53491 antikoerper, zgc:91795 antikoerper, gadd45a antikoerper, GADD45A antikoerper, ddit1 antikoerper, gadd45 antikoerper, GADD45 antikoerper, AA545191 antikoerper, Ddit1 antikoerper, DDIT1 antikoerper, Gadd45 antikoerper, growth arrest and DNA damage inducible alpha L homeolog antikoerper, growth arrest and DNA-damage-inducible, alpha, b antikoerper, growth arrest and DNA damage inducible alpha antikoerper, growth arrest and DNA damage-inducible protein 45 antikoerper, growth arrest and DNA-damage-inducible 45 alpha antikoerper, growth arrest and DNA-damage-inducible, alpha antikoerper, gadd45a.L antikoerper, gadd45ab antikoerper, GADD45A antikoerper, gadd45a antikoerper, GADD45 antikoerper, Gadd45a antikoerper

Hintergrund: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 20 kDa/25 kDa

Calculated_MW: 14 kDa/18 kDa

Gen-ID: 1647

UniProt: P24522

Pathways: p53 Signalweg, Zellzyklus