COL1A1 Antikörper

Produktnummer ABIN7250383

Produktdetails anti-COL1A1 Antikörper

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser COL1A1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: Monoclonal Antibody

Aufreinigung: Protein A purification

Immunogen: Synthetic Peptide of Collagen I

Klon: 3C3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu COL1A1

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Andere Bezeichnung: COL1A1 (COL1A1 Produkte)

Synonyme: OI4 antikoerper, Col1a-1 antikoerper, Cola-1 antikoerper, Cola1 antikoerper, Mov-13 antikoerper, Mov13 antikoerper, COLIA1 antikoerper, col1a1 antikoerper, MGC52532 antikoerper, COL1A1 antikoerper, COL1A2 antikoerper, alpha1(I) antikoerper, cb21 antikoerper, sb:cb21 antikoerper, sb:cb384 antikoerper, wu:fa99c12 antikoerper, wu:fb02c06 antikoerper, alpha3(I) antikoerper, col1a3 antikoerper, hm:zeh0348 antikoerper, wu:fa95h05 antikoerper, wu:fd02a10 antikoerper, wu:fj59a10 antikoerper, collagen type I alpha 1 chain antikoerper, collagen, type I, alpha 1 antikoerper, collagen, type I, alpha 1 S homeolog antikoerper, collagen alpha-1(I) chain antikoerper, collagen type I alpha 2 chain antikoerper, collagen, type I, alpha 1a antikoerper, collagen 1a1 antikoerper, collagen, type I, alpha 1b antikoerper, COL1A1 antikoerper, Col1a1 antikoerper, col1a1.S antikoerper, LOC397571 antikoerper, COL1A2 antikoerper, col1a1a antikoerper, col1a1 antikoerper, col1a1b antikoerper

Hintergrund: COL1A1 (Collagen Type I Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL1A1 include Caffey Disease and Osteogenesis Imperfecta, Type I. Among its related pathways are Collagen chain trimerization and Transcription_Role of VDR in regulation of genes involved in osteoporosis. GO annotations related to this gene include identical protein binding and platelet-derived growth factor binding. An important paralog of this gene is COL2A1.This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

UniProt: P02452

Pathways: Sensory Perception of Sound, Autophagie, Growth Factor Binding