9530092O11Rik antikoerper, ADAM-TS5 antikoerper, ADAMTS1 antikoerper, ADAMTS11 antikoerper, AI481094 antikoerper, ASMP-2 antikoerper, ADAM-TS 11 antikoerper, ADAM-TS 5 antikoerper, ADAMTS-11 antikoerper, ADAMTS-5 antikoerper, ADMP-2 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 5 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 5 antikoerper, ADAMTS5 antikoerper, adamts5 antikoerper, Adamts5 antikoerper
Hintergrund
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.