NMDA Receptor Synaptonuclear Signaling and Neuronal Migration Factor (NSMF) (AA 230-280) Antikörper

Produktnummer ABIN6991817

Produktdetails

Target: NMDA Receptor Synaptonuclear Signaling and Neuronal Migration Factor (NSMF)

Bindungsspezifität: AA 230-280

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: NELF Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal NELF antibody was raised against a 17 amino acid peptide near the center of human NELF. The immunogen is located within amino acids 230 - 280 of NELF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NELF antibody can be used for detection of NELF by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NELF Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NELF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Antigendetails

Target: NMDA Receptor Synaptonuclear Signaling and Neuronal Migration Factor (NSMF)

Andere Bezeichnung: NELF (NSMF Produkte)

Synonyme: HH9 antikoerper, NELF antikoerper, NMDA receptor synaptonuclear signaling and neuronal migration factor antikoerper, NSMF antikoerper

Hintergrund: NELF Antibody: NELF (nasal embryonic luteinizing hormone-releasing hormone factor) is a 530 amino acid transcription factor involved in the migration of LHRH neurons, outgrowth of olfactory axons and suppression of transcription elongation. NELF is found in the peripheral and central nervous system during embryonic development, and is highly expressed in adult testis, kidney and brain. Known to couple NMDA receptor signaling to the nucleus, NELF knockdown impaired GnRH neuronal migration of NLT cells in vitro and the gene encoding NELF has been linked to the development of Idiopathic hypogonadotropic hypogonadism (IHH), a disorder resulting in impaired pubertal maturation and reproductive function.

Molekulargewicht: Predicted: 58 kDa

Gen-ID: 26012

NCBI Accession: NP_056352

UniProt: Q6X4W1

Pathways: Synaptic Membrane