LMX1A Antikörper (C-Term)

Produktnummer ABIN6991775

Produktdetails anti-LMX1A Antikörper

Target: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Bindungsspezifität: AA 300-350, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMX1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: At least two isoforms are known to exist. This antibody is predicted to not cross-react with LMX1B.

Aufreinigung: LMX1A Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal LMX1A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LMX1A. The immunogen is located within amino acids 300 - 350 of LMX1A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LMX1A antibody can be used for detection of LMX1A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LMX1A Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LMX1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LMX1A

Target: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Andere Bezeichnung: LMX1A (LMX1A Produkte)

Synonyme: Lmx1.1 antikoerper, dr antikoerper, dreher antikoerper, sst antikoerper, LMX1 antikoerper, LMX1.1 antikoerper, si:ch211-260g14.3 antikoerper, LIM homeobox transcription factor 1 alpha antikoerper, LIM homeobox transcription factor 1, alpha antikoerper, Lmx1a antikoerper, LMX1A antikoerper, lmx1a antikoerper

Hintergrund: LMX1A Antibody: The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.

Molekulargewicht: 42 kDa

Gen-ID: 4009

NCBI Accession: NP_796372

UniProt: Q8TE12

Pathways: Dopaminergic Neurogenesis