AP3M1 Antikörper (C-Term)

Produktnummer ABIN6991550

Produktdetails anti-AP3M1 Antikörper

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Bindungsspezifität: AA 340-390, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AP3M1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: AP3M1 antibody may cross-react with AP3M2.

Aufreinigung: AP3M1 Antibody is affinity chromatography purified via peptide column.

Immunogen: AP3M1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human AP3M1. The immunogen is located within amino acids 340 - 390 of AP3M1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AP3M1 antibody can be used for detection of AP3M1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AP3M1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AP3M1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu AP3M1

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Andere Bezeichnung: AP3M1 (AP3M1 Produkte)

Synonyme: 1200013D09Rik antikoerper, C78982 antikoerper, R75378 antikoerper, P47a antikoerper, adaptor related protein complex 3 mu 1 subunit antikoerper, adaptor-related protein complex 3, mu 1 subunit antikoerper, AP3M1 antikoerper, Ap3m1 antikoerper

Hintergrund: AP3M1 Antibody: The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.

Gen-ID: 26985

NCBI Accession: NP_036227

UniProt: Q9Y2T2