SLC39A14 Antikörper (AA 230-280)

Produktnummer ABIN6991461

Produktdetails anti-SLC39A14 Antikörper

Target: SLC39A14 (Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14))

Bindungsspezifität: AA 230-280

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: At least three isoforms of ZIP14 are known to exist, this antibody will detect both isoforms. ZIP14 antibody is predicted to not cross-react with other ZIP family members.

Aufreinigung: ZIP14 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZIP14 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP14. The immunogen is located within amino acids 230 - 280 of ZIP14.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ZIP14 antibody can be used for detection of ZIP14 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ZIP14 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ZIP14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SLC39A14

Target: SLC39A14 (Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14))

Andere Bezeichnung: ZIP14 (SLC39A14 Produkte)

Synonyme: LZT-Hs4 antikoerper, NET34 antikoerper, ZIP14 antikoerper, cig19 antikoerper, BC021530 antikoerper, G630015O18Rik antikoerper, Zip14 antikoerper, fad123 antikoerper, solute carrier family 39 member 14 antikoerper, solute carrier family 39 (zinc transporter), member 14 antikoerper, SLC39A14 antikoerper, Slc39a14 antikoerper

Hintergrund: ZIP14 Antibody: The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

Molekulargewicht: Predicted: 54 kDa

Observed: 52 kDa

Gen-ID: 23516

NCBI Accession: NP_001128625

UniProt: Q15043

Pathways: Transition Metal Ion Homeostasis