NLRC5 Antikörper (N-Term)

Produktnummer ABIN6991398

Produktdetails anti-NLRC5 Antikörper

Target: NLRC5 (NLR Family, CARD Domain Containing 5 (NLRC5))

Bindungsspezifität: AA 20-70, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRC5 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: NOD4 antibody is predicted to not cross-react with other members of the NOD family of proteins.

Aufreinigung: NOD4 Antibody is affinity chromatography purified via peptide column.

Immunogen: NOD4 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NOD4. The immunogen is located within amino acids 20 - 70 of NOD4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NOD4 antibody can be used for detection of NOD4 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NOD4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NOD4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NLRC5

Target: NLRC5 (NLR Family, CARD Domain Containing 5 (NLRC5))

Andere Bezeichnung: NOD4 (NLRC5 Produkte)

Synonyme: NOD4 antikoerper, CLR16.1 antikoerper, NOD27 antikoerper, AI451557 antikoerper, AK220210 antikoerper, NLR family CARD domain containing 5 antikoerper, NLR family, CARD domain containing 5 antikoerper, NLRC5 antikoerper, nlrc5 antikoerper, Nlrc5 antikoerper

Hintergrund: NOD4 Antibody: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κ,B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

Molekulargewicht: 205 kDa

Gen-ID: 84166

NCBI Accession: NP_115582

UniProt: Q86WI3