Angiotensin II Type 2 Receptor Antikörper (AA 220-270)

Produktnummer ABIN6991187

Produktdetails anti-Angiotensin II Type 2 Receptor Antikörper

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Bindungsspezifität: AA 220-270

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin II Type 2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: AGTR2 Antibody is affinity chromatography purified via peptide column.

Immunogen: AGTR2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR2. The immunogen is located within amino acids 220 - 270 of AGTR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AGTR2 antibody can be used for detection of AGTR2 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunocytochemistry start at 5 μ,g/mL. For immunofluorescence start at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AGTR2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AGTR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Angiotensin II Type 2 Receptor

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Andere Bezeichnung: AGTR2 (AGTR2 Produkte)

Synonyme: AT2 antikoerper, ATGR2 antikoerper, MRX88 antikoerper, AI316812 antikoerper, AW107640 antikoerper, AT2-R antikoerper, AT2R antikoerper, AT₂R antikoerper, at2 antikoerper, zgc:113016 antikoerper, AGTR2 antikoerper, angiotensin II receptor type 2 antikoerper, angiotensin II receptor, type 2 antikoerper, AGTR2 antikoerper, Agtr2 antikoerper, agtr2 antikoerper

Hintergrund: AGTR2 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Molekulargewicht: Predicted: 40 kDa

Observed: 36 kDa

Gen-ID: 186

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones