LRFN1 Antikörper (C-Term)

Produktnummer ABIN6991075

Produktdetails anti-LRFN1 Antikörper

Target: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Bindungsspezifität: AA 700-750, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRFN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: This antibody is predicted to not cross-react with other members of the LRFN family.

Aufreinigung: LRFN1 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRFN1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LRFN1. The immunogen is located within amino acids 700 - 750 of LRFN1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LRFN1 antibody can be used for detection of LRFN1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LRFN1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LRFN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LRFN1

Target: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Andere Bezeichnung: LRFN1 (LRFN1 Produkte)

Synonyme: SALM2 antikoerper, BC004018 antikoerper, Semo1 antikoerper, leucine rich repeat and fibronectin type III domain containing 1 antikoerper, LRFN1 antikoerper, Lrfn1 antikoerper

Hintergrund: LRFN1 Antibody: LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.

Gen-ID: 57622

UniProt: Q9P244

Pathways: Synaptic Membrane